Rating: R for disturbing elements including strong sexuality, nudity, sci-fi violence and language
Release Date
June 4th, 2010
Director
Vincenzo Natali
Writers
Vincenzo Natali, Antoinette Terry Bryant, Doug Taylor
Starring
Sarah Polley, Adrien Brody, Delphine Chanéac
Studio
Senator Entertainment
Genre
Horror, Sci-Fi, Thriller
About Splice
Clive and Elsa are superstars of the genetic engineering world. They specialize in splicing together DNA from different animals to create fantastical new hybrids. The charismatic couple wants to use human DNA in a new hybrid – something that could yield astronomical medical benefits. The pharmaceutical company that funds their research, however, is more interested in exploiting their earlier triumphs for easier, short-term profit. Clive and Elsa secretly conduct their own experiment. The result is Dren: an amazing creature who exhibits an array of unexpected developments, both physical and intellectual. Dren exceeds their wildest dreams… and, ultimately, their most terrifying nightmare.
Splice was written by director Vincenzo Natali and screenwriters Doug Taylor and Antoinette Terry Bryant. The script was originally meant to follow up Natali’s Cube (1997), but the budget and restricted technology hindered the project. In 2007, the project entered active development as a 75% Canadian and 25% French co-production, receiving a budget of $26 million. The director described the film: “Splice is very much about our genetic future and the way science is catching up with much of the fiction out there. “[This] is a serious film and an emotional one. And there’s sex… Very unconventional sex. The centerpiece of the movie is a creature which goes through a dramatic evolutionary process. The goal is to create something shocking but also very subtle and completely believable.”
In October 2007, actors Adrien Brody and Sarah Polley were cast into the lead roles. Production began the following November in the city of Toronto. It was aided by Telefilm Canada’s funding of US$2.5 million. Filming took place in Toronto and Hamilton, Ontario and concluded in February 2008.
The creatures in the film were created by New York based artist Dan Ouellette of Neurotica Divine.
The film premiered on October 6, 2009 at Sitges Film Festival, where it won “Best Special Effects” and was in the running for “Best Film”, and was part of the 2010 Sundance Film Festival in Park City, Utah. After a bidding war with Apparition, The Weinstein Company, Newmarket Films, First Look Studios, and Samuel Goldwyn Films, Dark Castle Entertainment purchased the film in February 2010. The film will receive a wide release in the United States on June 4, 2010, with Warner Bros. as distributor. The trailer was attached to A Nightmare on Elm Street.
Early promo photos of Delphine Chanéac nude as the sexy but dangerous full-grown Dren leaked online very early, which eventually became Russian and German one-sheet posters for the film.


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